Detalhe da pesquisa
1.
Apolipoprotein C3 induces inflammasome activation only in its delipidated form.
Nat Immunol
; 24(3): 408-411, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36781985
2.
Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development.
Am J Hum Genet
; 102(1): 103-115, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29290336
3.
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.
N Engl J Med
; 378(12): 1096-1106, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29562163
4.
Rapid response to the alpha-1 adrenergic agent phenylephrine in the perioperative period is impacted by genomics and ancestry.
Pharmacogenomics J
; 21(2): 174-189, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168928
5.
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
N Engl J Med
; 377(3): 211-221, 2017 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28538136
6.
Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.
N Engl J Med
; 374(12): 1123-33, 2016 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26933753
7.
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.
N Engl J Med
; 374(12): 1134-44, 2016 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26934567
8.
Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.
Circ Res
; 120(2): 341-353, 2017 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899403
9.
Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.
Hum Mol Genet
; 25(24): 5500-5512, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28426890
10.
Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network.
Am J Hum Genet
; 97(4): 512-20, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26365338
11.
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
Am J Hum Genet
; 94(2): 223-32, 2014 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24507774
12.
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
Am J Hum Genet
; 94(2): 233-45, 2014 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24507775
13.
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.
Am J Hum Genet
; 93(3): 545-54, 2013 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23972371
14.
Effect of Genetic African Ancestry on eGFR and Kidney Disease.
J Am Soc Nephrol
; 26(7): 1682-92, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25349204
15.
Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.
Hum Mol Genet
; 22(12): 2529-38, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23446634
16.
Incorporating temporal EHR data in predictive models for risk stratification of renal function deterioration.
J Biomed Inform
; 53: 220-8, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25460205
17.
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future.
Genet Med
; 15(10): 761-71, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23743551
18.
Prescriber Adoption of SLCO1B1 Genotype-Guided Simvastatin Clinical Decision Support in a Clinical Pharmacogenetics Program.
Clin Pharmacol Ther
; 113(2): 321-327, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36372942
19.
Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm.
PLoS One
; 18(5): e0283553, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37196047
20.
Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn's Disease.
Sci Rep
; 11(1): 5595, 2021 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33692434